Which neurotransmitter changes are associated with Intermittent Explosive Disorder?

Individuals with Intermittent Explosive Disorder (IED) often exhibit low levels of serotonin. This deficiency in serotonin is thought to contribute to the impulsivity and aggressive behaviors characteristic of the disorder. Serotonin plays a crucial role in regulating mood, aggression, and impulse control, and low levels can lead to difficulties managing emotional responses, resulting in explosive outbursts.

Research in neurobiology has identified that individuals with IED frequently show abnormalities in serotonin function, which may lead to increased aggression and irritability. Additionally, treatments that enhance serotonin levels, such as selective serotonin reuptake inhibitors (SSRIs), have been utilized and shown to help mitigate the symptoms of IED, further underscoring its connection to serotonin dysregulation. This understanding aligns with the observed behavioral symptoms in IED and supports the selection of low levels of serotonin as the correct answer.